Skin effects build slowly
For the treatment-regimen estimand, the mean body weight reductions from baseline at 72 weeks were 15.0%, 19.5%, and 20.9% in the tirzepatide 5, 10, and 15 mg groups, respectively, versus 3.1% in the placebo group
For cognitive impairment, FDA-approved options include donepezil and the newer anti-amyloid antibodies for Alzheimer disease
Chao et al
Most scales dont differentiate between weight/fat loss & muscle loss, for that reason, tracking only your weight isnt a reliable way to determine whether youre losing weight, fat, or muscle & in what amounts Conversely, a body fat scale can provide a more accurate picture of your body composition by measuring the percentage of all components Be sure to measure yourself on a weekly or bi-weekly schedule to understand the changes that are happening
Extra B vitamins, especially B12, can give you a lot of energy, making it tough to fall asleep