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10.1186/s13195-018-0451-2 459 VoigtR

cytokines also are involved in various neural interactions such as neurogenesis and synaptic plasticity.1718 In this regard, neuroinflammation is distinguished from systematic inflammation

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A detailed review of literature has found increased oxidative stress in acute as well as chronic infections of the ear, nose, and sinuses and the rationale for adding an antioxidant to the therapy (126)

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Intrathecal administration of low doses significantly mitigated allodynia caused by sciatic nerve ligation, while high doses provided prolonged antinociceptive effects (454)