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May Cause Problematic Interactions with Some Medications

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Vitamin B12, and vitamin B2 are also important to the function of MTHFR in the folate cycle (Garcia-Minguillan et al, 2014) along with folate

Medication Use Certain medications, such as proton pump inhibitors (PPIs) for acid reflux or metformin for diabetes, can interfere with B12 absorption

Taken together, significant spine trauma creates an altered mechanical, cellular and metabolic status and may lead to cell death and malfunction of the disc compartments

These taxa form a pathogenic synergistic network: Prevotella provides metabolic substrates through carbohydrate degradation, Fusobacterium enhances biofilm structural stability to facilitate persistent colonization, and Porphyromonas secretes virulence factors that damage periodontal tissues and suppress host immunity