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Hence, melanocytes are one of the different types of cutaneous cells that contain massive amounts of ROS [13]

doi: 10.3389/fphar.2026.1740609 Received 06 November 2025 Revised 03 February 2026 Accepted 11 February 2026 Published 24 February 2026 Volume 17 - 2026 Edited by Ziyi Wang, Johns Hopkins University, United States Reviewed by Xue Xiaoyong, Beijing University of Chinese Medicine, China Yatan Li, Xinjiang Medical University, China Updates Copyright 2026 Pang, Jiang, Ge, Huang, Rao, Wang, Zhou, Lyu, Wang and Tan

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Understanding how they compare to emerging alternatives provides valuable context for anyone making decisions about treatment

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However, we use the PiQo4 on nearly all tattoos as black ink is used in shading and exists in nearly all tattoos, and PiQo4 is the fastest and safest laser for removing black on all skin types