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These macrophages, when activated by TLR ligands and interferon-, release proinflammatory cytokines such as TNF- and IL-6, which contribute to the progression of MASLD and systemic IR by modulating other immune cells (64) (Table 1)

doi:10.2146/ajhp120291 Strom BL, Schinnar R, Apter AJ, Margolis DJ, Lautenbach E, Hennessy S, Bilker WB, Pettitt D

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