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Beyond weight loss, the expanding therapeutic landscape of GLP-1 agonists now includes cardiovascular risk reduction, peripheral artery disease management, and active clinical trials for neurodegenerative disorders and substance use disorderswith over 15 global trials underway for the latter indication alone
These medications are generally reserved for patients with severe osteoporosis or those who have not responded adequately to anti-resorptive therapy
December 5, 2025
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