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The patches are little at first, but they will eventually get bigger

Conditional weighted residuals (CWRES) were used as a diagnostic tool to identify outliers, and an additional 24 concentration values (23 in the one-compartment model) were excluded from the final dataset as they were associated with CWRES greater than 6 in order to limit bias from influential data items

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When these spaces expand, harmful substances freely enter the bloodstream and can cause an aggressive immune system response

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This includes, the patient with intracardial tumor mass with SD at start of therapy