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SODs administration has also been reported to alleviate inflammatory, infectious, respiratory, metabolic and cardiovascular diseases and genitourinary and fertility disorders, raising the question of its mechanism of action in these diverse situations

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In a Phase 2 trial published in the New England Journal of Medicine in 2023, participants taking the highest dose of retatrutide lost an average of 24.2 percent of their body weight over 48 weeks

Moreover, since the TMAO increase was limited to a period of 6 months, we cannot exclude that different effects could be observed in conditions of chronic TMAO elevation

Huang, CN., Wang, CJ., Lin, CL., Lin, HT., Peng, CH

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