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[DOI] [PubMed] [Google Scholar] 64.Mosenzon O, Blicher TM, Rosenlund S, Eriksson JW, Heller S, Hels OH, Pratley R, Sathyapalan T, Desouza C PIONEER 5 Investigators
April 2025
What Bowel Changes Can Look Like Constipation usually means fewer than three bowel movements per week, hard or lumpy stool, straining, or a sense that you did not fully empty your bowels
Order one to two vials ahead at most, timed so each new vial arrives within a week or two of when you need it
Published in the New England Journal of Medicine, it enrolled 751 adults with obesity but without type 2 diabetes