Regulatory profile as a research landmark Semaglutide is one of the more fully characterized compounds in its class, with a regulatory record spanning multiple formulations
Semaglutide, the active ingredient in Ozempic and Wegovy, works by mimicking glucagon-like peptide-1 (GLP-1), a hormone that regulates hunger and blood sugar simultaneously
Tirzepatide Brand names: Mounjaro, Zepbound How it works: This drug impersonates two hunger-regulating hormones: GLP-1 and GIP
Potential Risks and Considerations Even if milk transfer is minimal, semaglutide can still indirectly impact breastfeeding by: Causing rapid weight loss that affects maternal energy and nutrition
Limitations Nasal sprays lower bioavailability results in 30%-50% less systemic exposure compared to injection, based on pharmacokinetic sampling in current trials
However, weight loss can naturally slow down over time, which is known as a plateau