The results show that overall in both control and diseased retinas, ROS generation due to photo-oxidation, quantified by r , drives large changes in the level of the [GSH]/[GSSG] ratio, exerting a negative effect, which indicates that this process is potentially a great contributor to increased oxidative stress
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The proline concentration was determined using a calibration curve 48
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These experiments support the notion that MK-801 does not enhance the pharmacokinetics of gut peptides and that the additional metabolic benefits and synergistic weight loss effects brought about by MK-801 are dependent on NMDA receptor antagonism in GLP-1-receptor-positive neurons
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