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A physician must review the patients diagnosis, medications, side-effect risk, kidney and liver function, diabetes status, blood pressure, cholesterol, and overall treatment goals

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The focus during this phase often pivots from scale numbers to body composition refinement and skin quality improvement

This low entry point reflects clinical trial protocols and real-world practice patterns that prioritize gradual introduction of the medication's dual mechanism

Yet, the mechanisms they employ have complimenting approaches in managing metabolic health

These three neuropeptides act on distinct and complementary targets