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In pre-clinical research, inhibiting NNMT is studied for its effects on NAD+ salvage pathway activity and methyl-donor availability

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Mice given extra GLP-1 (via gene therapy or a GLP-1 agonist drug) developed more oxidative, fatigue-resistant muscle fibers (more Type I fibers), built up greater muscle glycogen stores, and increased mitochondrial biogenesis changes that enhanced their endurance performance (1)

36 , e00285 (2015) Wootten, D

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Heres why this temperature range is ideal: 1