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E.RaqeebA.Della CorteA.CinelliM.MontagnaniS.et al (2013)

B12 injections are generally very safe with minimal side effects

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Some patients experience low energy in the first few weeks, particularly during dose increases

After first reconstitution (puncturing the rubber stopper with a sterile needle to introduce bacteriostatic water), the vial's internal environment is exposed, though the rubber stopper reseals when the needle is removed

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