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421 Specifically, dysfunction within the ventrolateral periaqueductal gray (vlPAG)-mediated descending pain modulatory system has been reported in patients with PDPN

Dietary fibre, particularly soluble types, stimulates GLP-1 release through short-chain fatty acids produced by gut bacteria fermenting fibre

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MDA, a by-product of ROS-induced lipid peroxidation, has also been found in higher serum concentrations in hypothyroid patients (79)