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Nevertheless, it has been shown that in the humans, the GST with the highest activity toward AFB 1 exo-epoxide is the polymorphic hGSTM1-1 which is absent in about 50% of individuals in most human populations
It adds that clinical data on the strategy is still emerging
Amgen, Viking Therapeutics, Boehringer Ingelheim, Zealand Pharma, and Pfizer are also important watchlist companies