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7.3.6 Clinical translation Successful translation of ferroptosis-targeted therapies requires methodical progression through several key stages: validation of candidate biomarkers in well-characterized human cohorts, optimization of inhalation formulations for consistent pulmonary deposition, and demonstration of safety and efficacy through rigorously designed clinical trials

PBMCs were allowed to recover for 1 h at 37 C in RPMI medium supplemented with 10% FCS before RNA isolation

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About 12% of American adults are currently taking a GLP-1 medication for weight loss or type 2 diabetes treatment