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Oxidized-LDL (ox-LDL) retained in the arterial wall represents the initial injury that, through interaction with the endothelial lectin-type ox-LDL receptor 1 (LOX-1), activates the inflammatory response to injury with the involvement of innate and adaptive immunity

Green tea epigallocatechin-3-gallate inhibits angiogenesis and suppresses vascular endothelial growth factor C/vascular endothelial growth factor receptor 2 expression and signaling in experimental endometriosis in vivo

For future exploration, an immediate goal is to develop selective ZDHHC inhibitors as well as novel pharmacological APT protein inhibitors

No evidence of significant endocrine disruption, hepatic, or cardiovascular adverse effects has been observed in available data when used within researched dose ranges

McCann UD, Wong DF, Yokoi F, Villemagne V, Dannals RF, Ricaurte GA (1998)