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However, NCBSO and free BSO, which did not have GSH-responsive properties, did not show obvious cytotoxicity within the given concentration range

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This modification allows the peptide to bind to amylin receptor subtypes 1 and 3 in the brain, specifically in the area postrema of the hindbrain, producing sustained appetite reduction without the peaks and valleys that come with shorter-acting compounds

Tang, W

Advanced nanomedicines for the treatment of inflammatory diseases

Liang S, Gu Y