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When NCOA4 expression is upregulated, it recognizes and binds to ferritin heavy chain 1 (FTH1) and mitochondrial ferritin (FTMT), interacting with autophagy-related factors and primary autophagosomes to form autophagosomes for lysosomal degradation, thereby releasing large amounts of Fe 2+ and forming the LIP

Correll CU, Newcomer JW, Silverman B, et al

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Fish oil and omega-3s Omega-3 fatty acids, such as DHA and EPA, are essential building blocks for a healthy brain and may offer protection against damage to brain cells