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Aged mice (12 months, roughly equivalent to middle age in humans) administered MOTS-c for four weeks showed improved physical performance, grip strength, and metabolic markers compared to controls

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Front Nutr 12:1522287 [DOI] [PMC free article] [PubMed] [Google Scholar] 54.Park BS, Henning PC, Grant SC, Lee WJ, Lee SR, Arjmandi BH et al (2013) HMB attenuates muscle loss during sustained energy deficit induced by calorie restriction and endurance exercise

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