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10.1016/j.kint.2023.05.024 Kidney Int

Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages

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The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism

Nevertheless, there are still some obstacles to translating these preclinical data into human clinical trials, mainly related to the dosage regime (dose, interval and duration), and pharmacokinetics, particularly bioavailability issues, and these aspects should be the main focus of future research