Collectively, these findings suggest that GLP-1R activation may have a protective role in schizophrenia, anxiety disorders, autism, and bipolar disorder, though further validation through non-genetic epidemiological studies and clinical trials is warranted
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N Engl J Med 375(4):311322 Mannucci E, Candido R, Delle Monache L, Gallo M, Giaccari A, Masini ML, Mazzone A, Medea G, Pintaudi B, Targher G, Trento M, Turchetti G, Lorenzoni V, Monami M (2022) Italian guidelines for the treatment of type 2 diabetes
PCOS/PMOS (polycystic ovary syndrome): Hormonal imbalances and insulin resistance can make weight loss more challenging
Whether the trajectory continues through Phase 3's 72-week treatment period is one of the open questions
Hypoxia promotes non-small cell lung cancer cell stemness, migration, and invasion via promoting glycolysis by lactylation of SOX9