In general, improvement in verbal communication was significantly greater in participants on folinic acid as compared with those on placebo for participants with abnormal folate metabolism (i.e., FRAA positive, low glutathione redox ratio)
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Journal of Public Health Management and Practice, 30(5)
Interestingly, SOD is an antioxidant enzyme that promotes the breakdown of O 2 radical into O 2 and H 2 O 2 , thereby annihilating oxidative damage ( 2 O 2 and lipid hydroperoxides, as well as direct neutralization of AFT (by forming an AFTGSH conjugation) ( are built up, which aggressively attack the phospholipid membrane, leading to MDA accumulation ( Accordingly, oxidative damage is prominently emphasized in our study, expounded by an evident drop in GSH levels and the activities of SOD and GPx in renal tissues
doi: 10.3390/jcm13216292 53 HoganAEGaoatsweGLynchLCorriganMAWoodsCOConnellJet al