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Rare but serious side effects may include pancreatitis or gallbladder problems

Researchers compared the percentage of body weight loss after 3, 6, 9 and 12 months of treatment among adults who received intensive lifestyle modification, non-GLP-1 receptor agonist pharmacotherapy or GLP-1 receptor agonists as part of a weight-loss program, with both pharmacotherapy groups also utilizing intensive lifestyle modification

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Deepali Anand April 22, 2026 Our experts continually monitor the health and wellness space, and we update our articles when new information becomes available

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Adding a second drug adds a second contraindication list and a second adverse-effect profile without adding trial evidence