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For example, DAMPs such as HMGB1, S100A8/A9, cfDNA, and oxidized low-density lipoprotein (oxLDL) can interact with TLRs, leading to the activation of NF-B and IRF3 pathways through MyD88-dependent or -independent mechanisms

While glutathione supplements and topical creams are utilized, IV glutathione is widely recognized as the most effective means to deliver this potent antioxidant

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