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doi: 10.3390/cells12030505 [DOI] [PMC free article] [PubMed] [Google Scholar] 94

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In addition, non-pharmacological interventions for gout, including dietary modifications, weight management, and physical therapies, demonstrate multi-target efficacy by reducing serum uric acid levels, modulating inflammatory pathways, and improving metabolic parameters, thereby decreasing flare frequency, preventing complications, and complementing pharmacotherapy in mild-to-moderate cases

Hydrogen peroxide production was measured using the Amplex-red specific probe ( Figures 2A,B )