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At 28 weeks, berobenatide demonstrated dose-dependent decreases in A1C up to 2.2% and in body weight of up to 10.2% with a slope that continued to decrease weekly, said Ildiko Lingvay, MD, MPH, MSCS, Professor in the Department of Internal Medicine, University of Texas Southwestern Medical Center

Mar 3 2011;364(9):818-828

While the company likely has research programs exploring oral delivery, no oral tirzepatide formulation has entered Phase 3 trials (the final stage before FDA approval)

These occur in less than 1% of patients but require immediate medical attention if they develop

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