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When taken in high doses, it is used for skin whitening due to its melanin-reducing effects

By precisely targeting the hypoxic TME, these biomaterials offer a dual advantage: restoring radiosensitivity at the tumor core while simultaneously sparing healthy pelvic organs from collateral damage [42, 43]

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Aguiar-Oliveira, M

Additionally, recent evidence suggests that melatonin secretion patterns in NS workers are associated with differential DNA methylation in melatonin receptor gene MTNR1A and other circadian genes, potentially linking altered melatonin rhythms to increased cancer susceptibility 196

Signal transduction pathway through activin receptors as a therapeutic target of musculoskeletal diseases and cancer