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This suggests that variations in the techniques used, biological samples analyzed, timing of sampling, and subject selection may be the cause of discrepancies (Geyik et al., 2016

Summary Keywords acute lymphoblastic leukemia, methotrexate, glutathione, metabolomics, drug resistance, arsenic trioxide, thioredoxin reductase Citation Canevarolo RR, Melo CPS, Cury NM, Artico LL, Corra JR, Lau YT, Mariano SS, Sudalagunta PR, Brandalise SR, Zeri ACM and Yunes JA (2022) Glutathione levels are associated with methotrexate resistance in acute lymphoblastic leukemia cell lines

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MAIT cells MAIT cells are a unique subpopulation of innate invariant T cells, distinguished by the expression of an evolutionarily conserved invariant T cell receptor alpha (TCR) chain

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485 Additionally, overexpressing ABCB8, a mitochondrial protein that promotes iron export, reduces both mitochondrial ROS and iron, improving DOX-induced cardiomyopathy