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For individuals who want to maintain normal eating patterns, avoid central appetite manipulation, cannot tolerate GLP-1 side effects, or prefer targeted fat metabolism enhancement without hunger modification, AOD-9604 offers an alternative mechanism

ShahabMHSaifullah KhanS

Mechanistic studies in mice show anti-inflammatory and anti-atherogenic effects, including direct attenuation of T-cell-mediated inflammation via gut receptors and indirect modulation of myeloid cell activity through central neuronal pathways

doi: 10.1172/JCI99934

They share some benefits, like helping with energy production, but have clear differences too