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Because they increase GH/IGF-1 signaling, potential side effects overlap with GH elevation generally: Neither CJC-1295 nor ipamorelin is FDA-approved as a medication for anti-aging, body composition, or recovery

17:733 Hochstrasser T, Ullrich C, Sperner-Unterweger B, Humpel C (2011) Inflammatory stimuli reduce survival of serotonergic neurons and induce neuronal expression of indoleamine 2,3-dioxygenase in rat dorsal raphe nucleus organotypic brain slices

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As a result of these synthetic forms, immunoassays that are able to differentiate endogenous IGF-1 from the therapeutic forms have become highly sought after

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