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Senescent cells accumulate with aging and after acute stresses like chemotherapy, secreting inflammatory mediators collectively termed the senescence-associated secretory phenotype (SASP)

Supplements worth considering during the higher dose phases include a quality multivitamin (to cover micronutrient gaps from reduced food intake), vitamin D (often depleted during significant weight loss), B vitamins for energy metabolism, and magnesium for muscle function and sleep quality

These include: Importantly, many of these complications are technique-dependent

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