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In The Lancet 2023 trial (Frias et al.), once weekly co administration (CagriSema) was reported to result in greater weight loss than semaglutide alone or cagrilintide alone , with tolerability described within the protocol context

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One study found that paracetamol t 1/2 was prolonged in very early pre-terms (2832 weeks gestational age), suggesting that the dose interval may need to be extended in this group, although only a single dose was given [47]

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