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Moreover, ferroptosis mechanisms are predominantly investigated in I/R or nephrotoxic AKI models, with limited data on sepsis-induced, metabolic (e.g., diabetic), or autoimmune AKI subtypes

Halpert, G

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PMID: 21672938 Sajewicz W, Milnerowicz S, Nabzdyk S

However, these medications have several important limitations: (1) delayed onset of therapeutic action, typically requiring weeks to months for clinical effect