What were discovering is that GLP-1 receptors are not just present in the brain, gut and pancreas
A 2021 review published in Biomedicine & Pharmacotherapy explains that silymarin, the main active compound in milk thistle, can:25 Regulate the cell cycle, helping to ensure proper division and replication Induce apoptosis, or programmed cell death, by which the body can eliminate mutated cells (e.g., cancer cells) Regulate the body's immune response, increasing its ability to recognize and attack cancer cells Keep tumor cells from growing and spreading Inhibit angiogenesis, the process by which tumors create new blood vessels that increase their blood supply and help them grow The review specifically discusses silymarin's therapeutic potential for gastrointestinal cancer, but as another set of researchers note, silymarin has a pleiotropic effect, meaning it can act on multiple targets.26 Again, more research may be needed, but the current science suggests that milk thistle may have fairly broad complementary utility in cancer therapy
Originally Developed for Diabetes: The Shift to Weight Management Originally designed for blood sugar control in type 2 diabetes, GLP-1 drugs have evolved into important therapies for obesity treatment globally
While not approved for clinical use, CJC-1295 has become a central point of investigation in lab-based models focused on endocrine signaling and cellular regeneration
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Qian et al., 2025)
