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Given that a function of glycolysis is consistent with the control of redox homeostasis, the data is consistent with prior studies that demonstrated that glyercol-3-phosphate can be a major contributor of substrate-fuelled mitochondrial ROS production 29
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In our previous study, we showed that the Tyr 98 residue in the caddie protein, which is accommodated in the pocket of active center of tyrosinase, is converted to a reactive quinone through the formations of the - 2 : 2 -peroxo-dicopper(II) and Cu(II)-dopasemiquinone intermediates