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The pharmaceutical companies extensive marketing of these drugs (with Novo Nordisk and Eli Lilly commanding market dominance and generating billions in annual revenue) created widespread exposure among both diabetes patients and those seeking weight loss

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Severe abdominal pain, particularly if it radiates to the back, could indicate pancreatitis, a rare but serious adverse event associated with GLP-1 therapy

doi: 10.3760/cma.j.cn112142-20231025-00184, 21

Most ease within a few weeks or after a dose hold

[1] [2] The weight loss observed with Rybelsus typically occurs gradually over several months, with clinical trials (PIONEER programme) demonstrating average reductions of 3-5% of body weight when used for diabetes management