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Many women have been taught from adolescence that menstrual pain is normal and something to endure silently (Culley et al., 2013)

The key difference is that tirzepatide generally produces more weight loss, more quickly, which means the adjustment period may be more pronounced but the long-term sleep benefits (from greater weight loss and sleep apnea improvement) may also be greater

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Moreover, adequate safety margins were observed in repeat-dose rat and monkey toxicology studies, which supported advancing PF-06882961 to human clinical studies

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