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Due to the miniaturization of the flow chambers and the limitations of the membranes, the conventional dynamic BBB models were mostly discontinued

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Vit-B12 is also an essential nutrient for skeletomusculargutbrain axis to maintain skeletal muscle, neuro-cognitive functions, and modulate gut microbiota 550,551

A significant reduction in glucose levels was detected after 30 min toward baseline at time 120 in the treated GDM rats (LBN and HBN groups), whereas a consistently high concentration of glucose was found during 30120 min in the GDM rats