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2018 Feb 14;7(1):1823

Front Physiol 3:260 Fabbri et al., J Gerontol 2020 Chronic cytokine activity ( IL-6, TNF- ) accelerates frailty and sarcopenia via persistent low-grade inflammation linking metabolic aging with musculoskeletal decline

Just as people with diabetes stay on insulin or metformin indefinitely, individuals with obesity benefit from ongoing GLP-1 support

Cardiovascular benefit of SGLT-2 inhibitors and GLP-1 receptor agonists in the treatment of type 2 diabetes: a systematic review and reticulated Meta-analysis

Baseline peripheral blood biomarkers associated with clinical outcome of advanced melanoma patients treated with ipilimumab

Note that the therapeutic indication for all of these drugs is for type 2 diabetes, with the exception of Wegovy (2.4 mg/week of semaglutide by subcutaneous injection), which was recently approved for weight loss