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Giant colonic/sigmoid diverticulum (GCD) is a rare complication of diverticular disease in which a diverticulum reaches 4 cm or greater in diameter
Engineered live bacterial systems constructed through genetic modification and synthetic biology techniques can deliver therapeutic drugs to the liver or gastrointestinal tract [7], demonstrating certain advantages in enhancing local drug concentration and reducing systemic adverse reactions
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4% with placebo, and vomiting (5%, 7% and 14%) vs
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