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Study B, employing a crossover design, demonstrated that twice-daily PT-141 administration resulted in greater mean body weight reduction (1.7 kg) versus placebo (0.9 kg)

Biochem Biophys Res Commun 517(4):557565 Liang D, Zhuo Y, Guo Z, He L, Wang X, He Y, Li L, Dai H (2020) SIRT1/PGC-1 pathway activation triggers autophagy/mitophagy and attenuates oxidative damage in intestinal epithelial cells

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People considering adding B vitamins to their daily routine should talk with a doctor in advance.

Consult with a healthcare provider for a personalized recommendation