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Commenters stated that there was additional randomized controlled trial data from the Walter Reed Medical Center which reported a mean intraservice time of 32.2 minutes as compared with 20 minutes from the RUC survey

doi:10.1016/j.redox.2019.101223

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Yet, we noted that FUS-induced BBB opening combined with GSK-3 inhibitor delivery had an additive effect on plaques reduction efficiency reaching 39.6% reduction, compared to 15.1% with FUS-BBB opening alone and 22.6% with GSK-3 inhibitor administration alone (see Fig

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Jul 2015;13(7):1175-83