what's better than semaglutide A diabetes drug. Then a weight-loss drug. Then a global blockbuster. Here's how GLP-1s went from helping manage blood sugar to becoming one of medicine's biggest stories. [GLP-1, Ozempic, Wegovy, Mounjaro, diabetes Semaglutide vs Tirzepatide: Which Works

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They found that the administration of GLP-1 agonists is associated with a: 9.09 times higher risk of pancreatitis (inflammation of the pancreas) 4.22 times higher risk of bowel obstruction (a condition characterized by the obstruction of food passage through the small or large intestine, leading to symptoms such as abdominal cramping, bloating, nausea, and vomiting) 3.67 times higher risk of gastroparesis (stomach paralysis, a condition that restricts the passage of food from the stomach to the small intestine, resulting in symptoms such as vomiting, nausea, and abdominal pain) These results are similar to those of a study investigating the long-acting GLP-1 RA liraglutide

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Among the 496 metabolites, 159 species showed significant differences in abundance (Figure 4B)

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