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doi: 10.1016/S0923-2508(97)83621-2 153 HaditschU.RothT.RodriguezL.HancockS.CecereT.NguyenM.et al

doi: 10.1186/s10194-021-01271-1, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 10.Biscetti L, Cresta E, Cupini LM, Calabresi P, Sarchielli P

These agents specifically bind fungal iron transporters, enhancing drug targeting and reducing toxicity to host cells, thus improving both efficacy and safety

References Sikiric P, Seiwerth S, et al

These lipid hydroperoxides are unstable and can decompose into secondary oxidative products, such as aldehydes, alkanes, and ketones, with malondialdehyde (MDA) and 4-hydroxynonenal (4-HNE) being notable for their cytotoxic and mutagenic effects [51]

Targeting ferroptosis thus offers a promising avenue for precision oncology in renal cancer, warranting further development of selective inducers and biomarker-guided therapeutic regimens