If you have lost less than 5% of body weight after six months at maximum dose with good adherence, you may be a non-responder
Semaglutide (Ozempic, Wegovy, Rybelsus) is a prescription GLP-1 medication used for weight loss and weight management, type 2 diabetes treatment, or to reduce the risk of chronic kidney disease and major cardiovascular events in certain patients with type 2 diabetes
The medication may indirectly support ketosis by reducing carbohydrate cravings, which makes strict carb restriction easier to maintain
However, for patients who have already reached a healthy weight, microdosing may help maintain results while potentially providing ongoing metabolic benefits with fewer side effects
Bottom line Semaglutide medications like Ozempic, Wegovy, and Rybelsus are most effective when paired with a healthy, balanced diet
As a result, some individuals may experience initial feelings of fatigue, which typically diminish as the body adjusts to potential changes in diet