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The GLP-1 receptor is present in neurons and glial cells in several brain regions (Diz-Chaves et al., 2022b)

Additionally, semaglutide acts on receptors in the brain to reduce appetite and promote satiety, contributing to its weight loss effects

[PUBMED Abstract] Higano CS, Schellhammer PF, Small EJ, et al.: Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer

Accumulating evidence suggests that the ventral hippocampus contributes to the control of energy balance

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