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Pineal melatonin is synthesized in the absence of light (typically at night) under sympathetic control

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p = 0.1106) on measured level of GSSG (Fig

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Al residuo obtenido, aadir con precisin 1.0 mL de solucin acuosa de cido frmico al 0.1%, sonicar durante 1 min para disolver el residuo, filtrar a travs de un filtro de 0.22 m y analizar mediante cromatografa de lquidos-espectrometra de masas en tndem (LC-MS/MS)

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