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KWONG: OK, so Eli Lilly is putting their pill through clinical trials

When starting this medication, it is advised to slowly increase your dose until you reach 2.4 mg weekly with the intention of helping to reduce side effects

In patients receiving cagrilintide 2.4 mg plus semaglutide, there was a mean body weight change from baseline of -17.1% compared to -9.8% with semaglutide alone

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The pathomechanisms of obesity-associated MASLD include lipotoxicity, inflammation, fibrogenesis, and carcinogenic risk [39], suggesting that combating obesity is a major objective in treating MASLD

We also highlight areas for future research, such as the potential to target metabolic pathways and mediators therapeutically